• Medical_Professionals
• Medical_students
• Nurses

Defect in DNA damage repair and checkpoint control is the underlying mechanism for tumorigenesis, since it allows the accumulation of multiple genetic alternations, which are essential for the initiation of tumorigenesis. This has been clearly illustrated to be the cause of several human cancer-prone syndromes and also revealed by recent human genome studies. On the other hand, defective DNA repair and checkpoint activation also make cancer cells more vulnerable for particular DNA damaging agents or inhibitors that specifically disrupt some of these checkpoint pathways. With the increasing understanding of defects in DNA repair and checkpoint control in tumorigenesis, there are extensive interests in exploring these deficiencies, especially taking advantage of the synthetic lethality concept and targeting particular DNA repair and checkpoint pathways for cancer therapy. The purpose of this conference is to bring together basic, translational and clinical investigators and discuss the current and future directions, opportunities and obstacles in the development of these anti-cancer modalities and how to best apply these concepts in clinical practice.

Key Sessions

Highlight recent advances in the field of DNA damage repair

Identify novel targets in DNA repair and checkpoint pathways

Explore the concept of synthetic lethality for cancer treatment

Assess the therapeutic potential of new anti-cancer modalities

Learn mechanisms of therapeutic resistance and ways to improve cancer therapy

Jan van Deursen (Mayo Clinic)

Susan Domcheck (University of Pennsylvania)

Stephan Gasser (Roche)

Traver Hart (MD Anderson Cancer Center)

Stephen Kowalczykowski (UC Davis)

Lei Li (MD Anderson Cancer Center)

Jennifer Litton (MD Anderson Cancer Center)

Andre Nussenzweig (NCI)

Mark O'Connor (AstraZeneca)

Ketan J. Patel (MRC Laboratory of Molecular Biology)

David Pellman (Harvard University)

Abena Redwood (MD Anderson Cancer Center)

Agnel Sfeir (New York University)

Joann Sweasy (Yale University)

Johannes Walter (Harvard University)

Bin Wang (MD Anderson Cancer Center)

Xiaohua Wu (Scripps Research Institute)

Tim Yap (MD Anderson Cancer Center)

Xiaochun Yu (City of Hope)

Lee Zou (Massachusetts General Hospital)

Our registration fees are inclusive of the following during the conference period only:

- Conference registration 

- 3 Nights’ fixed accommodation (23, 24, 25 Feb 2019) on a single basis for academics and industry, on a shared basis for students/Postdocs

- Breakfast, lunch and dinner available at all restaurants according to their operational hours (excluding Black Angus and Starbucks)

- Unlimited select brand liquors, wines by the glass, local domestic beer, bottled water and soft drinks

- Gala Dinner (includes an open bar)

- Room service (note a delivery charge will be applied)

- Guest room mini bar

- Non motorized water sports equipment

- Complimentary WIFI in both conference rooms and your guest room

What\'s Included in our Accompanying Adult Fees?

Our accompanying adult fees are inclusive of the following during the conference period only:

- 3 Nights’ fixed accommodation (23, 24, 25 Feb 2019) on a shared basis with a conference participant 

- Breakfast, lunch and dinner available at all restaurants according to their operational hours (excluding Black Angus and Starbucks)

- Unlimited select brand liquors, wines by the glass, local domestic beer, bottled water and soft drinks

- Gala Dinner (includes an open bar)

- Room service (note a delivery charge will be applied)

- Guest room mini bar

- Non motorized water sports equipment

- Complimentary WIFI in your guest room

Important Note: Accompanying persons are not permitted access to the conference

USD

Group registrations not allowed

Accompanying persons not allowed

We don’t accept Online Abstracts

Melia Nassau Beach All Inclusive

Nassau, Bahamas

Venue Rating4 StarsCurrencyUS Dollar (USD)Nearest AirportLynden Pindling International Airport

Location Details

The Melia Nassau Beach All-Inclusive is located right on the stunning Cable Beach just a few minutes away from the airport and city center; Nearby in Downtown Nassau you can experience the flavours of new foods at local restaurants, shop 'til you drop at Straw market or take a trip through time at the Pirates Museum. The beautiful Nassau Botanical Gardens are close by and water enthusiasts can enjoy non-motorized water sports right on property.

Nassau is the capital of the Bahamas. It lies on the island of New Providence, with neighboring Paradise Island accessible via Nassau Harbor bridges. The city has a hilly landscape and is known for it's fabulous beaches as well as its offshore coral reefs, popular for diving and snorkeling. It retains many of its typical pastel-colored British colonial buildings, like the pink-hued Government House.

Submission Info

Office address

Unit 5D, Lynx Business Park

Fordham Road

Snailwell

Newmarket

CB8 7NY

United Kingdom

Office numbers

Tel: +44 (0) 1638 724137

Fax: +44 (0) 1638 724135

Office contact

Skype: Fusion.Conferences

Email: admin@fusion-conferences.com

• Diamond

  

• Media Partners

  

Office address

Unit 5D, Lynx Business Park

Fordham Road

Snailwell

Newmarket

CB8 7NY

United Kingdom

Office numbers

Tel: +44 (0) 1638 724137

Fax: +44 (0) 1638 724135

Office contact

Skype: Fusion.Conferences

Email: admin@fusion-conferences.com