• Medical_Professionals
• Medical_students
• Nurses

Cellular homeostasis is governed by complex RNA-protein interaction networks that control information flow. RNA metabolism is particularly complex in neurons, involving extensive diversification of gene expression through splicing and redistribution of RNA subsets to the distant compartments where they ultimately function. In recent years, perturbation of RNA metabolism has emerged as a consistent underlying defect in certain neurological diseases, suggesting that aspects of RNA metabolism that are unique to the nervous system may also create unique vulnerabilities.

This two-day symposium organized by Paul Taylor and Fen-Biao Gao will bring together basic and clinical scientists to discuss the role of perturbed RNA metabolism in neurological diseases, including amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), spinal muscular atrophy (SMA), and repeat expansion disorders.

Topics will include:

RNA binding proteins in the pathogenesis of neurological diseases

C9ORF72 repeat expansion in neurological disorders

Unconventional translation in repeat expansion diseases

RNA granules and axonal transport

Cellular and animal models of RNA defects

Emerging therapeutic approaches

USD

Group registrations not allowed

Accompanying persons not allowed

We don’t accept Online Abstracts

The conference will take place at Paradise Point Resort & Spa in San Diego, USA.

Tucked away on gentle Mission Bay in the heart of San Diego, Paradise Point Resort & Spa features comfortable bungalow-style rooms amidst lush, tropical gardens, tranquil lagoons, and one mile of sandy beach next door to SeaWorld.

Paradise Point and its amenities offer a unique location for the conference that is secluded, yet centrally situated with the airport, downtown San Diego and top attractions including Old Town, the San Diego Zoo, and Balboa Park all just minutes away.

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Chloe Partridge

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