The conference has been approved for 18 CME credits by the European Accreditation Council for Continuing Medical Education (EACCME). EACCME credits are recognised by the American Medical Association.
The conference has been approved for 18 CME credits by the European Accreditation Council for Continuing Medical Education (EACCME). EACCME credits are recognised by the American Medical Association.
Rotterdam is easy to reach in a variety of ways: by car, boat, train, bus and by air. Inside the city, a network of buses, trams, water taxis and metro maintains excellent connections and the city is small enough that it is usually easy to walk from one place to another. The ICCBH venue, De Doelen Conference Centre, is just 5 minutes on foot from Rotterdam Central Station and there are several hotels in the immediate vicinity or close by.
Please see this map showing the locations of the venues we will be using for the ICCBH along with the suggested accommodation options.
Amsterdam Schiphol Airport is only 25 minutes from Rotterdam by high speed trains which depart approximately every 20 minutes. There are direct flights to Schiphol from many of the world’s major cities.
In addition, Rotterdam is served by its very own airport, which is just 8 km / 5 miles north-west of the city centre.Rotterdam The Hague Airport is relatively small and features regular flights to many European cities. Regular bus transport is on hand and provides a cheap way to travel into the city centre, with a journey time of no more than 20 minutes.
The Thalys network offers a high-speed link from Paris through Belgium with up to 10 trains a day. Journey times have recently been cut and you can now travel from Paris to Rotterdam in just a little over two and half hours. Travellers from the UK can travel by Eurostar to Brussels then on with the Thalys.
Typical journey times:
Antwerp to Rotterdam 30 minutes
Brussels to Rotterdam 1 hour 11 minutes
Paris to Rotterdam 2 hours 36 minutes
Rotterdam is easily accessible by the A13, A15, A16 and A20 motorways. Once in the city there are a number of options for parking but it is important to note that on-street parking often requires a pre-paid card. For more about parking in Rotterdam please view here. The nearest car park to De Doelen is at Schouwburgplein but if you’re travelling from outside the city a Park & Ride location may be cheaper.
Cycling is an ideal way to explore the city, as it allows you to view many of Rotterdam's most important attractions in just a short space of time. To rent bikes visit Fietspoint Rotterdam CS located near Central Station. You can also take a guided tour of the city for example with Rotterdam ByCycle.
Within Rotterdam a network of buses, trams, water taxis and metro makes it easy to get around by public transport. All the information you need is on the web here.
It is our pleasure to invite you to the 6th International Conference on Children's Bone Health, to be held 22-25 June 2013 in the vibrant city of Rotterdam, Netherlands.
The aim of this Conference is to bring together scientists and clinicians from a wide range of disciplines to gain a better understanding of the growing skeleton in health and disease. The scope ranges from basic molecular mechanisms to clinical aspects, from bone physiopathology to treatment and we invite anyone with an interest in bone metabolism and bone mass in children, adolescents and young adults to attend.
The Conference Programme is designed to present researchers, physicians, and allied health professionals with an overview of state-of-the-art research, with plenary lectures by some of the world's leading experts in the field, as well as workshops, Round Table discussions on topics linked to paediatric bone health, and oral and poster sessions.
The Conference will offer investigators from around the world an opportunity to meet with each other and with industry representatives. There will be plenty of opportunity for discussion and we actively encourage you to submit your abstracts for oral and poster presentation. Our priority is to maximise the time available for presentation of submitted abstracts.
As the biggest seaport in Europe Rotterdam is one of the most important trading centres in the world. The city centre was largely destroyed during the Second World War and since then it has become a showcase for modern architecture with new and exciting buildings constantly under development – this is a confident city! There are numerous education institutes, including the Erasmus University and the Erasmus Medical Centre Rotterdam, the biggest medical centre in the Netherlands. Amsterdam’s Schiphol Airport is less than half an hour away by train, and on arrival the conference venue, De Doelen Congress Centre, and many hotels are all within 10-15 minutes’ walk of the rail station.
ICCBH is the premier venue to hear about state of the art clinical and basic science applicable to children's bone health. Come and participate in a lively interactive meeting with the leaders in the field!
We look forward to seeing you in Rotterdam in June 2013!
Maria Luisa Bianchi
Chair: International Programme Committee
Sabine de Muinck Keizer/Coen Netelenbos
Co-Chairs: Local Organising Committee
Judith Adams is Consultant Radiologist, Manchester Royal Infirmary and Honorary Professor of Diagnostic Radiology, Imaging Science & Biomedical Engineering (ISBE) at the University of Manchester, UK. She is a musculo-skeletal radiologist with a particular interest in metabolic bone disease (especially osteoporosis) and quantitative assessment of the skeleton. Her publications include 155 scientific papers, 20 reviews and 23 chapters and she has collaborated in over £3M research grants. Professor Adams has served as Dean (Vice President) of the Royal College Radiologists, Chairman of the Osteoporosis Group of the European Society of Skeletal Radiology (ESSR) and of the National Osteoporosis Society (NOS) Bone Densitometry Forum.
Paul Baldock is Senior Research Fellow and Group Leader of the Bone Regulation Group, Neuroscience Research Program,Garvan Institute of Medical Research, Sydney, Australia. He completed his PhD in Human Physiology at the University of Adelaide in 2001 and since then has gone on to win several awards. His areas of interest are bone mass, neuropeptide Y, bone strength, osteoporosis, leptin, and the hypothalamus.
Susanne Bechtold-Dalla Pozza is a Consultant Pediatric Endocrinologist working at the Department of Endocrinology and Diabetology of the Dr von Haunersches Kinderspital, Ludwig-Maximilians University, Munich, Germany. She completed her pediatric training at the department of Pediatrics at the University Children’s Hospital, Munich, following a clinical and research fellowship at the same institution. Her past and current research focuses on the influence of chronic diseases on growth and bone strength and density. She performed a 10 year study on GH treatment in juvenile idiopathic arthritis and the influence on bone and growth development. She received twice a grant for a one year scholarship each for excellent researchers from the Ludwig-Maximilians University.
She published more than 80 research papers and is a reviewer for about 20 international journals.
Dr Bianchi has been engaged in clinical activity and scientific research on bone metabolic diseases since the early 1980s. Dr Bianchi is currently working at the Istituto Auxologico Italiano IRCCS, a hospital and research institute in Milan, Italy. She has special interests in pathophysiology, problems of diagnosis and treatment of primary and secondary osteoporosis in children and adolescents; evaluation of adherence to treatment and quality of life in osteoporosis. Dr Bianchi has been a member of the ICCBH International Scientific Committee since 1997 and is on the Board of Directors of the International Bone and Mineral Society and the European Calcified Tissue Society (ECTS) and the Editorial Boards of Bone and Calcified Tissue International. She is author or co-author of over 200 scientific articles and book chapters.
The UK's only Professor of Paediatric Bone Disease, Nick Bishop trained in Manchester (clinical), Cambridge (MRC and Wellcome Fellowships) and Montreal (visiting Professor at McGill). He was appointed to Chair in Sheffield in 1998. In 2002 Nick was appointed Head of the Academic Unit of Child Health and in 2008 Directorof the Children’s Clinical Research Facility. He is also Director for Undergraduate Medical Education at the Sheffield Children’s NHS Foundation Trust. His clinical research group focuses on the treatment of childhood osteoporosis and his basic science group on pathophysiology of childhood bone diseases. Professor Bishop has been a member of the ICCBH International Scientific Committee since 1997 andorganised the 2002 and 2009 ICCBH meetings in Sheffield and Cambridge.
Annemieke M Boot is paediatric endocrinologist at University Medical Center Groningen – Beatrix Children’s Hospital in Groningen, the Netherlands. After her study she worked as general medical doctor in Blantyre and Mangochi in Malawi from 1989 to 1992, Africa. Her training of paediatrics and paediatric-endocrinology (head Prof dr SLS Drop) was in Sophia Children’s Hospital – Erasmus MC in Rotterdam, the Netherlands. Her research is focussed on bone mineral density and bone metabolism in children.She was awarded her PhD in 1997. She is a member of The European Society of Paediatric Endocrinology (ESPE) and is active in the ESPE Bone and Growth Plate working group.
I am a Consultant Senior Lecturer in Rheumatology at the University of Bristol, UK. My research area is Musculoskeletal Epidemiology, with a particular interest in the role of bone mass in determining fracture risk in children and adolescents. Other areas of interest are the epidemiology of hypermobility and scoliosis in adolescents, and identification of osteoporotic vertebral fractures in older adults. I am on the Editorial Boards of Therapeutic Advances in Chronic Diseases and Frontiers in Medicine. I am a member of the NIHR Health Technology Assessment Programme, and convene the British Society for Rheumatology Osteoporosis Special Interest Group. I have been a recipient of the American Society for Bone and Mineral Research (ASBMR) President’s Book Award.
Maja Di Rocco, MD,is Head of the Unit of Rare Diseases, Department of Pediatrics, at the IRCCS Gaslini, Genoa, Italy, and a professor of metabolic diseases at the Postgraduate Schools of Pediatrics, Medical Genetics, and Pediatric Neurology and Psychiatry at the University of Genoa. She graduated in medicine and surgery from the University of Genoa in 1979, before completing a postgraduate degree in paediatrics in 1983, and in paediatric neurology and psychiatry in 1987, at the same institution. In 1986 she completed a fellowship in the Department of Neurology at Columbia University, New York, NY, USA. Her research interests include the biochemical and molecular bases of inborn errors of metabolism, the treatment of lysosomal diseases, and the molecular bases of genetic diseases. She is a member of several national and international societies for Inborn Errors of Metabolism and Genetics and published over 160 original articles on metabolic and genetic matter in peer-reviewed journals.
Dr Paul Dimitri studied Medicine at the University of St Andrew’s in Scotland and the University of Manchester where he received a medal in pathology and a distinction in Paediatrics. In 2010 he was awarded a PhD in Medicine and the Michael Blacow Award from the Royal College of Paediatrics and Child Health for his work on the relationship of fat and bone in children. Paul currently works as a Consultant in Paediatric Endocrinology at Sheffield Children’s Hospital. He was appointed as the Director of Research and Innovation and the Deputy Director for the Medicines for Children Research Network (East of England) in 2012. Paul’s research interests include the effect of obesity on skeletal growth and the development of novel imaging of bone in children and adults.
Rachel I Gafni received her BA from Barnard College and her MD from Temple University. She completed a pediatric residency at the Children’s Hospital of Philadelphia followed by a pediatric endocrinology fellowship at the National Institutes of Health (NIH), serving as an officer in the Public Health Service from 1996-2002. She subsequently served as an Assistant Professor at the University of Maryland. Dr Gafni returned to NIH in 2007 as a staff clinician in the National Institute of Dental and Craniofacial Research. She is also faculty in the NIH Pediatric Endocrinology Training Program. She is an investigator on several protocols studying and treating patients with endocrine disorders including hypoparathyroidism, McCune-Albright Syndrome, hypophosphatemic rickets, tumoral calcinosis, and other metabolic bone diseases.
Dr Francis H Glorieux received his MD from the University of Louvain and his PhD from McGill University. It is there that he developed his interest in heritable pediatric bone diseases. His doctoral thesis focused on hypophosphatemic rickets and the demonstration that calcitriol and phosphate allowed for control of the bone disease, a regimen still used worldwide in such patients. Since 1992 he has documented the beneficial effects of bisphosphonate in severe forms of Osteogenesis Imperfecta. Programs based on the Montreal protocols are now used all over the world. For 40 years, he has been the Head of the Genetics Unit at the Montreal Shriners Hospital for Children and a Professor at McGill University. He is the recipient of numerous Awards, and in 2004 was made an Officer of the Order of Canada, the country’s highest honor for lifetime achievement.
Catherine M Gordon, MD, MSc is a Professor of Pediatrics at the Alpert Medical School of Brown University and is Director of the Division of Adolescent Medicine at Hasbro Children's Hospital. She is board-certified in adolescent medicine and pediatric endocrinology. She is on the Board of Directors for the International Society for Clinical Densitometry, and directs the Student Research Program co-sponsored by the American Pediatric Society and Society for Pediatric Research. Her clinical interests include bone loss in pediatric chronic disease, pediatric densitometry, disorders of vitamin D and calcium metabolism, and eating disorders. Her research focuses on the effect of malnutrition on bone loss including the early osteoporosis seen in adolescents with anorexia nervosa, cystic fibrosis, and inflammatory bowel disease.
Wolfgang Högler is a Consultant Paediatric Endocrinologist, heading the Department of Endocrinology & Diabetes at Birmingham Children’s Hospital, Birmingham, UK. Dr Högler is also Honorary Senior Lecturer at the School of Medical and Dental Sciences at the University of Birmingham, UK and current Chair of the ESPE Working Group on Bone and Growth Plate.
Dr Högler completed his paediatric training at the Department of Paediatrics at Innsbruck University Hospital in Innsbruck, Austria. Following a clinical and research fellowship at the Institute of Endocrinology and Metabolism, Children’s Hospital at Westmead, in Sydney, Australia, he worked as an Associate Professor in Paediatrics at the Medical University in Innsbruck, Austria before moving to the United Kingdom. Dr Högler’s current research focuses on novel measures of mobility, bone strength and density and growth disorders. His group is currently investigating the role of whole body vibration on mobility and bone strength in children with osteogenesis imperfecta, as well as the complications of the rare growth disorder ALS deficiency on glucose metabolism and bone strength, including novel treatment options. His commitment to postgraduate education has led him to chair the endocrine branch of the IPOKRaTES Foundation. He organizes paediatric endocrine specialist seminars across the globe.
After completing medical training at Charing Cross and Westminster Medical School, I specialized in adult rheumatology at the Wessex Deanery. During that time, I completed a PhD examining the maternal determinants of intra-uterine bone growth as part of an ARC Clinical Fellowship at the University of Southampton. In my last year of clinical training, I was fortunate to be awarded an ARC travelling fellowship and worked with the OA group in UCSF to study the role of vitamin D and bone in lower limb OA, a fantastic opportunity. Since my return to the UK, I have been appointed as Senior Research Fellow in Metabolic Bone Disease/Honorary Consultant Rheumatologist at Oxford and further extended my research into the role of vitamin D status in musculoskeletal disease, improving outcomes after fragility fracture as well as continuing work looking into the bone phenotypes in osteoarthritis. Balancing clinical and teaching, my direction of research is evermore linking the basic science with the key clinical issues in OA and OP.
Dr Jüppner is a Professor of Pediatrics at Harvard Medical School, chief of pediatric nephrology at Massachusetts General Hospital forChildren, and a senior member of the Endocrine Unit at Massachusetts General Hospital. His research focuses on the regulation of mineral ion homeostasis and bone metabolism, with a primary interest in the PTH/PTHrP receptor and understanding its role in bone, kidney and cartilage biology. He is furthermore interested in parathyroid hormone (PTH) and fibroblast growth factor 23 (FGF23), has developed assays to measure these hormones, and helped assess their role in patients with phosphate-wasting disorders and chronic kidney disease. For more than a decade, molecular genetic studies have been the main focus of his research. His laboratory identified the molecular defect of several inherited disorders, including pseudohypoparathyroidism type Ib, Jansen metaphyseal chondrodysplasia, infantile cortical hyperostosis, and several hypophosphatemic disorders. To explore the molecular basis of these and other inherited human disorders, he has collaborated with a large numbers of investigators and clinicians.
Dr Kirmani is an Assistant Professor in Medical Genetics and Pediatrics at Mayo Clinic, Rochester, MN. He received his medical degree from Dow Medical College, University of Karachi, Pakistan. He went to Mayo Clinic to pursue a residency in Pediatric & Adolescent Medicine, and stayed there for a fellowship in Pediatric Endocrinology. He went on to pursue further training in Medical Genetics and has been on staff at Mayo Clinic since 2009. His clinical and research interests include pubertal bone mass accrual, hereditary metabolic bone disease and connective tissue dysplasias.
Craig B Langman MD is the Isaac A Abt, MD Professor of Kidney Diseases and Tenured Professor of Pediatrics at the Feinberg School of Medicine, Northwestern University and Head, Kidney Diseases at the Ann and Robert H Lurie Children’s Hospital of Chicago. He has had a career-long interest in the understanding of genetic or acquired rare and ultra-orphan diseases of kidney and bone, including nephrolithiasis. He participates in creation of evidence-based medicine guidelines, and his research is funded through the National Institutes of Health in the areas of genetic stone disease, chronic kidney disease, and cystinosis. Dr Langman served as the Chair of the ICCBH meeting held in Montreal CA in 2007.
Dr Mary Leonard, MD, MSCE is a Professor of Paediatrics and Epidemiology at the Perlman School of Medicine at the University of Pennsylvania, and the Director of the Office of Clinical and Translational Research at the Children’s Hospital of Philadelphia. Her multidisciplinary research program is focused on the assessment of bone health in children, and the detrimental effects of glucocorticoid therapy, chronic kidney disease, muscle deficits, vitamin D deficiency and inflammation on bone development in chronic pediatric disease. Her research uses quantitative computed tomography and novel micro-MRI imaging techniques. Her research program is supported by multiple NIH investigator-initiated grants.
Dr Agnès Linglart is a Paediatric Endocrinologist working at the Bicetre Hospital in Paris, France. She coordinates the French Reference Center for Rare Disorders of Bone and Mineral Metabolism.
Associate Professor Munns is a Senior Staff Specialist in Bone and Mineral Medicine and Endocrinology at the Children’s Hospital at Westmead and Conjoint Associate Professor in the Sydney Medical School at the University of Sydney, Australia. Following the completion of his Paediatric and Endocrinology training at The Royal Children’s Hospital, Brisbane, Australia, Associate Professor Munns was Clinical Associate in Genetic and Metabolic Bone Disorders at the Shriners Hospital for Children, Montreal, Canada. He was awarded his PhD through the University of Queensland in 2004. Associate Professor Munns’ major clinical and research focus is the diagnosis and management of primary and secondary bone disorders in children.
J Coen Netelenbos is Emeritus Professor of Endocrinology in the Department of Internal Medicine at the VU University Medical Center (VUMC), Amsterdam, Netherlands. He is Author/Co-author of more than 200 scientific publications and Reviewer/member editorial advisory board of several international journals and reviewer of national/international grant applications for MRC’s. Professor Netelenbos holds several positions on national and international societies, including President and Chair of the Scientific Committee of the Dutch Osteoporosis Foundation. He organised the First International Symposium on Children's Bone Health in Maastricht, The Netherlands (4-7 May 1999), and has remained on the organising committee since.
Gerard Pals is Director of the Centre for Connective Tissue Research at the VU University Medical Center (VUmc) in Amsterdam, Netherlands. Following completion of his MSc in Biochemistry in Utrecht he completed his PhD training in Human Genetics in Amsterdam. In 1987 he held a position as Visiting Scientist/Professor at Wayne State University in Detroit, USA, and then as Research Scientist from 1989 to 1997 in the Department of Clinical Genetics at the VUmc. He directed the VUmc Molecular Diagnostic Laboratory from 1997 to 2007 when he took up his current position. He is active in many national and international societies, particularly those relating to Human Genetics.
Dr Farzana Perwad is an Assistant Professor at the Department of Pediatrics, University of California San Francisco. Dr Perwad’s research focuses on the regulation of vitamin D and phosphorus homeostasis in health and disease. Her research projects include investigating the pathophysiology of X-Linked Hypophosphatemia in mouse models of the human disease, and to study the molecular mechanisms of action of fibroblast growth factor-23 in the kidney.
Frank Rauch trained as a pediatrician at the Children’s Hospital of Cologne University, Germany, where he started working on pediatric bone disorders in Dr Schoenau's laboratory. He then performed a research fellowship on metabolic bone disorders at the Shriners Hospital for Children, Montreal, Canada. Since 2001 he has been a clinician scientist at the Shriners Hospital and he is an Associate Professor at the Department of Pediatrics of McGill University. Dr Rauch has published 140 peer-reviewed publications and since 2009 has been the Editor of the Journal of Musculoskeletal and Neuronal Interactions. His main research areas are muscle-bone interaction and heritable bone disorders in children.
Susanne Schmidt graduated with a medical degree from the University of Rostock (Germany) in 1996 and received her pediatric training in Germany, Norway and Sweden. Already during this time she became interested in pediatric inflammatory bowel disease and bone mineral density. After residency, she worked as a pediatric gastroenterologist in the region of Gothenburg (Sweden) and intermittently also at the tertiary centre of pediatric gastroenterology of Sahlgrenska University Hospital. At the Institute of Clinical Science at Sahlgrenska Academy she conducted clinical studies as part of her PhD work, and in 2010 she defended her PhD thesis with the title “Bone mineral density in pediatric inflammatory bowel disease”. Susanne moved very recently to New Jersey (USA), but remains involved in an ongoing project in Gothenburg focusing on the development of bone mineral density in patients with inflammatory bowel disease during the transition from adolescence into adulthood.
Marry van den Heuvel-Eibrink is Associate Professor of Pediatric Oncology at the Erasmus MC/Sophia Children’s Hospital, Rotterdam, Netherlands. She began her medical career with an MD from the University of Utrecht and following a number of years of clinical work in the pediatric oncology field completed her PhD in Rotterdam in 2001. Since 2009 Dr van den Heuvel-Eibrink has been Head of the “late effects after childhood cancer treatment” outpatient clinic. She is a member of the SIOP Renal Tumour Study Group (RTSG) Steering Committee, and Chair of the EWOG-MDS Study Group Protocol Committee of the DCOG. Her research is dedicated to translational research in pediatric oncology/hematology and the genetic variation of toxicity and late effects of childhood cancer, with a special interest in endocrine sequelae.
Kate Wesseling-Perry, MD, is an Assistant Professor in Pediatric Nephrology at UCLA.Her research is focused on understanding the regulation of skeletal mineralization in patients with all stages of chronic kidney disease. Her research interest is identifying the abnormalities in bone that lead to the early development of renal bone disease.
Dr Carmen Wilson received a PhD in Epidemiology from the University of New South Wales, Australia, in 2008 for research focusing on the late complications of anti-cancer therapies among individuals diagnosed with childhood cancer. She then worked for a short time as study coordinator for the New South Wales Childhood Cancer Survivor Study before coming to work in the Department of Epidemiology and Cancer Control at St Jude Children’s Research Hospital, Memphis, Tennessee in 2010. Dr Wilson’s studies have focused on examining genetic and treatment-related factors which modify the risk of long-term complications among cancer survivors. Dr Wilson is the principal investigator of several genome-wide association studies evaluating genetic variation associated with cardiac dysfunction, obesity, bone health and neurosensory impairments in childhood cancer survivors. Her work has been funded by the Rally Foundation.
23-26 June 2009, Cambridge, UK
21-24 June 2007, Montreal, Canada
11-14 May 2005, Sorrento, Italy
12-15 June 2002, Sheffield, UK
4-7 May 1999, Maastricht, Netherlands
A chance to catch up with colleagues and get a preview of the poster presentations.
A networking evening and opportunity to relax and enjoy discussions with collaborators old and new and to discover something of the flavour and culture of the exciting city of Rotterdam – this is an event not to be missed!
There is a wide variety of hotel accommodation available in Rotterdam within a short walking distance of the train station and the meeting venue, De Doelen Conference Center.
A number of hotels offer a discount for delegates attending the meeting, as listed below.
Exhibition and sponsorship opportunities are available.
Options include support for:
All supporters will be offered a company write-up on the website (desktop and mobile versions), in the final programme and on the USB flashdrive, and will also be acknowledged on slides at the meeting.
Contact: Janet Crompton , Conference Organizer